GH Secretagogues
Sermorelin
Scientific Profile
Sermorelin is a 29-amino acid peptide analog of growth hormone-releasing hormone (1-29). In vitro studies demonstrate high affinity binding to GHRH receptors, stimulating GH release through G-protein coupled mechanisms.
Animal research indicates dose-dependent GH secretion without significant tachyphylaxis. The peptide sequence represents the biologically active portion of native GHRH, maintaining receptor activation while reducing molecular size.