FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION.
PEPTICHEMS Research Grade Peptides
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GH Secretagogues

CJC-1295 with DAC

Scientific Profile

CJC-1295 with DAC is a modified GRF(1-29) analog carrying a Drug Affinity Complex — a maleimidopropionic acid group at the C-terminus that forms a covalent bond with serum albumin. In vitro studies demonstrate high affinity binding to GHRH receptors, with the same four amino acid substitutions that protect the No-DAC form from enzymatic degradation.

The distinguishing feature is the albumin conjugation: where the No-DAC form has a short half-life, the DAC version remains bound to circulating albumin, and animal models show sustained GHRH receptor activation over a substantially longer period. Research indicates this extended profile results in prolonged GH release rather than increased peak amplitude.

This profile was compiled in-house and is not part of the published compendium.

This compendium provides objective scientific information on research peptides based solely on published literature. All descriptions are limited to biochemical properties and mechanisms observed in in-vitro or animal studies, with no implications regarding human efficacy or therapeutic applications.