Tissue Repair & Regeneration
Glycyl-Histidyl-Lysine Copper Complex
Scientific Profile
GHK-Cu is a tripeptide-copper complex (glycyl-L-histidyl-L-lysine complexed with copper(II) ions). In vitro studies demonstrate its ability to stimulate collagen synthesis, glycosaminoglycan production, and angiogenesis. The peptide serves as a copper delivery system, enhancing copper-dependent enzymatic processes crucial for tissue remodeling.
Animal models show accelerated wound healing through increased expression of MMPs, growth factors, and extracellular matrix components. GHK-Cu also exhibits antioxidant properties through superoxide dismutase-like activity.