Tissue Repair & Regeneration
KPV (Lysine-Proline-Valine)
Scientific Profile
KPV is a tripeptide (Lys-Pro-Val) representing the C-terminal sequence of alpha-melanocyte stimulating hormone. In vitro studies demonstrate potent anti-inflammatory properties through inhibition of NF-κB signaling pathways. Research indicates KPV can suppress pro-inflammatory cytokine production in various cell types.
Animal models of colitis show significant reduction in inflammatory markers and tissue damage. The peptide exhibits high stability and cell permeability due to its small size and specific amino acid composition.
This compendium provides objective scientific information on research peptides based solely on published literature. All descriptions are limited to biochemical properties and mechanisms observed in in-vitro or animal studies, with no implications regarding human efficacy or therapeutic applications.