GH Secretagogues
GHRP-6
Scientific Profile
GHRP-6 (His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) is a synthetic hexapeptide growth hormone secretagogue. Research demonstrates its high affinity binding to GHS-R1a receptors, activating phospholipase C signaling pathways. In animal models, GHRP-6 stimulates GH release with minimal effect on cortisol, prolactin, or LH/FSH secretion.
The peptide exhibits orexigenic properties through hypothalamic NPY/AgRP neuron activation in experimental studies. Its D-amino acid content confers metabolic stability.
This compendium provides objective scientific information on research peptides based solely on published literature. All descriptions are limited to biochemical properties and mechanisms observed in in-vitro or animal studies, with no implications regarding human efficacy or therapeutic applications.