GH Secretagogues
IGF-1 LR3
Scientific Profile
IGF-1 LR3 is a modified form of insulin-like growth factor-1 with 13 additional amino acids at the N-terminus and substitution of arginine for glutamic acid at position 3. These modifications confer resistance to IGF-binding proteins, significantly extending its half-life in biological systems.
In vitro studies demonstrate enhanced receptor binding affinity and mitogenic properties compared to native IGF-1. Animal models show prolonged activation of the PI3K/Akt signaling pathway due to its reduced protein binding.
This compendium provides objective scientific information on research peptides based solely on published literature. All descriptions are limited to biochemical properties and mechanisms observed in in-vitro or animal studies, with no implications regarding human efficacy or therapeutic applications.