Metabolic & GLP-1 Analogues
Adipotide
Scientific Profile
Adipotide (CKGGRAKDC-GG-D(KLAKLAK)2) is a proapoptotic peptide designed to target the vasculature of adipose tissue. In murine models, Adipotide has demonstrated selective binding to prohibitin, a protein highly expressed on the surface of blood vessels supplying white adipose tissue.
This targeted approach induces apoptosis specifically in adipose tissue vasculature, resulting in rapid fat reduction in animal studies. The peptide's mechanism involves disrupting mitochondrial membranes in targeted endothelial cells.
This compendium provides objective scientific information on research peptides based solely on published literature. All descriptions are limited to biochemical properties and mechanisms observed in in-vitro or animal studies, with no implications regarding human efficacy or therapeutic applications.